NAPLEX Dumps 2023 - New NABP NAPLEX Exam Questions
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NEW QUESTION # 63
A Physician orders amiodarone 1 mg/min for six hours, then 0.5 mg/min thereafter. The patient's weight is
156 lbs. The concentration of the IV bag comes as 1.8 mg per ml. Calculate the infusion rate in mL/hr.
- A. 16.67mls/hr then 8.3mls/hr
- B. 30mls/hr then 15mls/hr
- C. 60mls/hr then 30mls/hr
- D. 33.33mls/hr then /16.67mls/hr
- E. 8.3mls/hr then 4.15mls/hr
Answer: D
Explanation:
Explanation
[1 mg/ 1 min] * 60min= 60mg/hr. 60 mg/hr * [1 mL/ 1.8 mg] = 33.33 mL/hr 0.5 mg/min * [60 min/ 1 hr] = 30 mg/hr 30 mg/hr * [1 mL/1.8 mg] = 16.67 mL/hr Infusion rates: 33.33 mL/hr for 6 hours, then 16.67 mL/hr
NEW QUESTION # 64
Which of the following should be monitored when a patient is on SGLT2 inhibitor?
- A. Blood glucose
- B. Blood pressure
- C. Hydration status
- D. Renal function
- E. All of the above
Answer: E
Explanation:
Explanation
Because SGLT2 inhibitors work by preventing reabsorption of glucose in the kidneys, this increases frequency of urination. All of the options are monitoring requirements since the hydration status, blood pressure, blood glucose, and renal function may all be changed from increased urination (from the mechanism of the drug).
NEW QUESTION # 65
JM is a 32-year-old women who comes to your diabetic clinic with complain of several episodes of hypoglycemia. She is on Insulin NPH/regular 70/30, 22 units twice a day with breakfast and dinner. 8 units with lunch.
After discussing with physician you decide to decrease the total daily insulin by 10% and change to insulin glargine once a day and Insulin Lispro three time a day at ratio of 50:50 - 50 % of long and 50 % of short acting insulin.
What is her new insulin regimen? Round down to the nearest 1 unit.
- A. 30 units of insulin glargine once daily, Insulin Lispro 6 units 3 times a day with meals
- B. 18 units of insulin glargine once daily, Insulin Lispro 6 units 3 times a day with meals
- C. 15 units of insulin glargine once daily, Insulin Lispro 5 units 3 times a day with meals
- D. 16 units of insulin glargine once daily, Insulin Lispro 4 units 3 times a day with meals
- E. 23 units of insulin glargine once daily, Insulin Lispro 7 units 3 times a day with meals
Answer: E
Explanation:
Explanation
22 * 2 + 7 = 51 units of total insulin per day. Decrease by 10% 51 units * 0.9 = 45.9 units per day round up to
46 units. 46 units * 0.50 = 23 units, administer 23 units of insulin glargine once daily. 46 units * 0.50 = 23 units total Insulin Lispro. Round down, divided by three times a day, 7 units 3 times a day with meals.
NEW QUESTION # 66
You get an order for 5% amino acid 15% dextrose premixed parenteral nutrition solution, 2 L at 83mls/hr.
Your pharmacy technician tells you there is manufacture's backorder on those. How many ml of 20% dextrose would you need to provide the same amount of dextrose in 24 hrs?
- A. 200ml
- B. 1500ml
- C. 1000ml
- D. 1400ml
- E. 2500ml
Answer: B
Explanation:
Explanation
15% dextrose = 15gm/100ml = 300gm/2000ml. Patient needs 300gm. 300gm/Xml = 20gm/100ml = 1500ml
NEW QUESTION # 67
Which of the following is/are ordinal data?
- A. Improvement Yes/No
- B. Sex
- C. NYHA I-IV
- D. Grade of breast cancer
- E. Alive or Dead
Answer: D
Explanation:
Explanation/Reference:
Explanation:
Categorical data includes ordinal (ordered categories) and nominal (unordered categories). NYHA I-IV and grade of breast cancer are considered ordinal data because the categories for the answer choice are in order, you can have NYHA class I, II, III, or IV. Grade of breast cancers are also in order, grade 1, 2, or 3. Sex, Improvemnet Yes/No, Alive or Dead is considered nominal, unordered data because the answer choices are female or male, and do not have a set order.
Reference:
http://www.bmj.com/about-bmj/resources-readers/publications/statistics-square-one
NEW QUESTION # 68
Injectable Sulfamethoxazole/Trimethoprim comes as 400mg/80mg/5ml. Physician requests you to dose a Sulfamethoxazole/Trimethoprim intravenously for PCP. You know the dose is 15mg/kg/day (based on TMP component) divided q6h.
How many milliliters of Sulfamethoxazole/Trimethoprim of 400mg/80mg/5ml would you need for single dose? Patient weighs 80kg.
- A. 16.5 mL
- B. 18.75 mL
- C. 50 mL
- D. 75 mL
- E. 15 mL
Answer: B
Explanation:
Explanation
80kg person = 15mg/kg/day = 1200mg/day 80mg /5ml = 1200mg/X X= 75mL/day / 4 doses = 18.75 mL per dose
NEW QUESTION # 69
FT is a 23-year-old newly diagnosed type I diabetes admitted to the hospital due to diabetes ketoacidosis. 2 days after being on insulin drip, anion gap is closed. Physician would like your help in transitioning her to subcutaneous insulin. She suggests using insulin glargine once a day and Insulin lispro three time a day at ratio of 70:30. 70 % of long and 30 % of short acting insulin. FT received average of 70 units of insulin in 24hrs.
Which of the following would be the best insulin regimen?
- A. 46 units of Insulin Glargine subcutaneous daily and 8 units of Insulin Lispro subcutaneous three times a day with meals
- B. 25 units of Insulin Glargine subcutaneous daily and 15 units of Insulin Lispro subcutaneous three times a day with meals
- C. 49 units of Insulin Glargine subcutaneous daily and 7 units of Insulin Lispro subcutaneous three times a day with meals
- D. 40 units of Insulin Glargine subcutaneous daily and 10 units of Insulin Lispro subcutaneous three times a day with meals
- E. 52 units of Insulin Glargine subcutaneous daily and 6 units of Insulin Lispro subcutaneous three times a day with meals
Answer: C
Explanation:
Explanation
70% of 70 units = 49 units of Insulin Glargine daily 30% of 70 units = 21 units of Insulin Lispro daily. Dived in 3 doses would be 7 units three times a day. FT's Insulin regimen should be 49 units of Insulin Glargine subcutaneous daily and 7 units of Insulin Lispro subcutaneous three times a day with meals
NEW QUESTION # 70
A patient takes 1gm of Calcium Carbonate salt three times a day. How much elemental calcium, in grams, is he getting in 24hrs? (MW of Ca: 40.078 g/mol, MW of CaCO3: 100.087 g/mol)
- A. 1.8mg
- B. 1.2g
- C. 3 g
- D. 1.8g
- E. 0.8gm
Answer: B
Explanation:
Calcium makes up 40% of the MW of CaCO3. MW Ca / MW CaCO3 40.078 / 100.087 × 100% = 40%. 40% of 1 g CaCO3 = 0.4 g. Patient is taking 0.4 g of Ca 3 times daily. 0.4 g Ca × 3 = 1.2 g of Elemental Ca.
NEW QUESTION # 71
Which of the following medication can lower seizures threshold?
- A. Thiothixene
- B. Bupropion
- C. All of the above can lower seizure threshold
- D. Clozapine
- E. Tramadol
Answer: C
Explanation:
Seizure threshold can be lowered by bupropion, chlorpromazine, clozapine, maprotiline, olanzapine, thioridazine, thiothixene, and tramadol.
NEW QUESTION # 72
Concomitant use of warfarin and omeprazole is associated with increased INR and prothrombin time(PT).
What enzyme dose the omeprazole inhibits that is metabolized by warfarin?
- A. CYP3A4
- B. CYP2C19
- C. CYP2C9
- D. CYP1A2
- E. CYP2D9
Answer: B
Explanation:
Explanation
Omeprazole is CYP2C19 inhibitor which can prolong the elimination of warfarin, particularly R-warfarin. R- warfarin is partially metabolized by CYP2C19. The combined use of omeprazole and warfarin has been associated with reports of increased INR and prothrombin time (PT).
NEW QUESTION # 73
A patient presents in the pharmacy in a delirious state with pinpoint pupils. Which of the following toxicity states does the patient most likely have?
- A. Opioid
- B. Alcohol
- C. Benzodiazepine
- D. Amphetamine
Answer: A
Explanation:
Explanation
Signs of opioid overdose include pinpoint pupils, delirious state, nausea / vomiting, respiratory depression and sleepiness or loss of consciousness. Naloxone may be used to reverse the effects of opioid overdose.
NEW QUESTION # 74
A 22-year-old woman adopted a cat. Shortly thereafter, she developed itchy eyes and persistent rhinorrhea.
She was clearly allergic to the pet, but desperately wanted to keep it. She tried taking diphenhydramine, but it had intolerable side effects.
Which of the following is a common effect of this type of medication?
- A. Excessive sweating
- B. Diarrhea
- C. Xerostomia
- D. Decreased intraocular pressure
- E. Bradycardia
Answer: C
Explanation:
Explanation
Diphenhydramine possesses anticholinergic properties. Xerostomia, or dry mouth, is a common side effect of anti-cholinergic medications, due to anti-muscarinic, parasympatholytic effects. Other adverse reactions may include: * Mydriasis with blurred vision, photophobia * Urinary retention * Constipation * Anhidrosis * Hyperthermia * Tachycardia * Altered mental status A commonly referenced mnemonic for anti-cholinergic toxicity is "mad as a hatter, red as a beet, dry as a bone, hot as a hare, blind as a bat" to reflect confusion, flushing, dry mouth, hyperthermia and mydriasis, respectively.
NEW QUESTION # 75
Number of new cases per population at risk in a given time period is a definition of which of the following?
- A. Odds ratio
- B. Mortality rate
- C. Incidence rate
- D. Prevalence rate
- E. Confidence Interval
Answer: C
Explanation:
Incidence rate = New reported cases / summed person-years of observation (avg population during time interval). Prevalence = Cases in a population in a given time period / total population at that time Mortality rate
= deaths during specified time interval / population size at risk for death.
Reference:
https://www.cdc.gov/ophss/csels/dsepd/ss1978/lesson3/section2.html
NEW QUESTION # 76
LN is 84 YOM who is in hospital for a back surgery. His height is 5 feet and 4 inches, weight 85 kg and NKDA. His past medical history includes hypertension, diabetes mellitus, major depression, hypothyroidism and chronic back pain.
Post-op day 1, LN's medication includes Dexamethasone 8 mg iv q6h with taper dosing, Ondansetron 4 mg iv q6h prn for N/V, Levothyroxine 0.075 mg po daily, Lisinopril 10 mg po daily, Citalopram 20 mg po daily, Docusate sodium / Senna 1 tab po twice a day, Bisacodyl 10 mg suppository daily prn for constipation, Famotidine 20 mg iv q12hr, Metoclopramide 10 mg iv q6h, Metformin 500 mg po bid, D51/2NS with 20 K at
125 mls/hour and Hydromorphone PCA at 0.2 mg/hour of basal rate, demand dose 0.1 mg. lock-out every 6 min, one hour limit 2.2 mg/hour. Pertinent morning labs includes serum creatinine 1.4 mg/dl, Mg 1.5 mg/dl, K
5.0 mmol/L, Na 135 mmol/L.
Which of the following medication may increase LN's Blood glucose?
- A. Lisinopril
- B. Famotidine
- C. Dexamethasone
- D. Metoclopramide
- E. Hydromorphone
Answer: C
Explanation:
Explanation
Dexamethasone can increase LN's blood glucose. All glucocorticosteroids are known to increase blood glucose. Blood glucose would need to be monitored while LN is being treated with dexamethasone.
NEW QUESTION # 77
Which of the following class of antidiabetic medication may cause fluid retention?
- A. Bile acid sequestrant
- B. GLP-1 agonist
- C. Thiazolidinediones
- D. Alpha-glucosidase inhibitor
- E. SGLT2 Inhibitor
Answer: C
Explanation:
Thiazolidinediones may cause fluid retention through proposed mechanism of increasing reabsorption in the collecting duct of the kidney and increasing vascular permeability in adipose tissue. Bile acid sequestrants work in the intestine to bind bile acids which doesn't affect fluid retention. GLP-1 receptor agonists work to activate these receptors to secrete insulin from beta pancreatic cells/decrease glucagon secretion/ increase satiety and doesn't affect fluid retention. SGLT2 inhibitors actually cause increase of fluid elimination through the kidneys.
Alpha-glucosidase inhibitors work in the gut to decrease carb absorption/digestion and have no affect on fluid retention.
NEW QUESTION # 78
If a patient takes 0.5mg of intravenous hydromorphone every 4hrs what would be the equivalent orals total daily dose? Hydromorphone oral to parenteral ratio 7.5:1.5.
- A. 15mg
- B. 5mg
- C. 10mg
- D. 7.5mg
- E. 20mg
Answer: A
Explanation:
Explanation
To determine the dose conversion IV to PO, the ratio of PO to IV needs to be determined, this is 7.5 / 1.5 which is 5. This number means that the PO dose is 5 times more than the IV dose to get the same amount of drug into the bloodstream. If the patient is taking 0.5 mg IV then the PO dose would be 0.5 mg multiplied by
5, which is 2.5 mg. Since the patient is taking the medication every 4 hours the patient is receiving 6 doses,
24hrs/4hrs = 6. Since the patient is receiving 2.5 mg every dose and is receiving 6 doses a day, the patient is receiving 15 mg, 2.5 mg multiplied by 6 doses.
NEW QUESTION # 79
A Physician orders Dobutamine HCl IV infusion at 5 mcg/kg/min. Dobutamine HCl is available as 500 mg in
250 mL of D5W. The patient weighs 68 kg. Calculate the infusion rate in mL/hr.
- A. 22.4mls/hr
- B. 340mls/hr
- C. 10.2mls/hr
- D. 5.2mls/hr
- E. 0.17mls/hr
Answer: C
Explanation:
Explanation
68 kg * [5 mcg/kg/min] = 340 mcg/min Bag concentration = 2 mg/ml or 2000 mcg/ml 340 mcg * [1 mL/2000 mcg] = 0.17 mL/min 60 in * [0.17 mL/min] = 10.2 mLs in one hour
NEW QUESTION # 80
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The NAPLEX exam is designed to assess the knowledge and skills of individuals who have completed a pharmacy degree program and are seeking licensure as a pharmacist. NAPLEX exam covers a wide range of topics related to the practice of pharmacy, including drug therapy, patient care, pharmacology, and pharmaceutical calculations. NAPLEX exam is computer-based and consists of 250 multiple-choice questions.
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